The Wildlife Healthcare & Research Centre (WHRC) was opened in March 2006. It is a two-level facility that aims to enhance research and conservation capabilities of animals in Singapore Zoo and Night Safari. The Centre has advanced and new facilities such as the treatment room, surgical room, x-ray room, animal wards and post-mortem room. This allows proper and better medical care for the animals. On top of that, this new infrastructure provides better support for research programmes for the WRS Parks and overseas partners. WHRC aims to excel in veterinary healthcare and research, training of Zoo vets, and reproductive research in Zoo animals.

The centre is aims to educate the public about the importance of the health of wildlife. There is a gallery present in the centre for visitors to learn more about veterinary practices and cases. With this, visitors are more aware of the care and effort required by wildlife and they may be able to better relate to wildlife in a more humanistic manner.