Category: 2011 – 2015

Publications

Year 2011 – 2015

  1. Zhao X, Xiong S, Huang LC, Ng KW,Loo SCJ. Nanoparticle-assay marker interaction: effects on nanotoxicity assessment. Journal of Nanoparticle Research 17, (2015) [https://doi.org/10.1007/s11051-014-2841-0].
  2. Zhao X, Lui YS, Choo CKC, Sow WT, Huang CL, Ng KW, Tan LP,Loo JSC. Calcium phosphate coated Keratin-PCL scaffolds for potential bone tissue regeneration. Materials Science and Engineering C 49, 746-753, (2015) [https://doi.org/10.1016/j.msec.2015.01.084].
  3. Wang X, Sng MK, Foo S, Chong HC, Lee WL, Tang MBY, Ng KW, Luo B, Choong C, Wong MTC, Tong BMK, Chiba S, Loo SCJ, Zhu P,Tan NS. Early controlled release of peroxisome proliferator-activated receptor β/δ agonist GW501516 improves diabetic wound healing through redox modulation of wound microenvironment. Journal of Controlled Release 197, 138-147, (2015) [https://doi.org/10.1016/j.jconrel.2014.11.001].
  4. Wang S, Wang Z, Foo SEM, Tan NS, Yuan Y, Lin W, Zhang Z,Ng KW. Culturing fibroblasts in 3D human hair keratin hydrogels. ACS Applied Materials and Interfaces 7, 5187-5198, (2015) [https://doi.org/10.1021/acsami.5b00854].
  5. Satish R, Vanchiappan A, Wong CL, Ng KW,Srinivasan M. Macroporous carbon from human hair: A journey towards the fabrication of high energy Li-ion capacitors. Electrochimica Acta 182, 474-481, (2015) [https://doi.org/10.1016/j.electacta.2015.09.127].
  6. Liu H, Zhang Z, Toh WS, Ng KW, Sant S,Salgado A. Stem Cells: Microenvironment, Micro/Nanotechnology, and Application. Stem Cells International 2015, 1-2, (2015) [https://doi.org/10.1155/2015/398510].
  7. Kathawala MH, Yun Z, Chu JJH, Ng KW,Loo SCJ. TiO2-nanoparticles shield HPEKs against ZnO-induced genotoxicity. Materials and Design 88, 41-50, (2015) [https://doi.org/10.1016/j.matdes.2015.08.108].
  8. Kathawala MH, Ng KW,Loo SCJ. TiO2 nanoparticles alleviate toxicity by reducing free Zn2+ ion in human primary epidermal keratinocytes exposed to ZnO nanoparticles. Journal of Nanoparticle Research 17, (2015) [https://doi.org/10.1007/s11051-015-3068-4].
  9. Kathawala MH, Khoo SPK, Sudhaharan T, Zhao X, Say Chye Loo J, Ahmed S,Ng KW. Fluorescence techniques used to measure interactions between hydroxyapatite nanoparticles and epidermal growth factor receptors. Biotechnology Journal 10, 171-179, (2015) [https://doi.org/10.1002/biot.201400404].
  10. Hartrianti P, Ling L, Goh LMM, Ow KSA, Samsonraj RM, Sow WT, Wang S, Nurcombe V, Cool SM,Ng KW. Modulating Mesenchymal Stem Cell Behavior Using Human Hair Keratin-Coated Surfaces. Stem Cells International 2015, (2015) [https://doi.org/10.1155/2015/752424].
  11. George S, Ho SS, Wong ESP, Tan TTY, Verma NK, Aitken RJ, Riediker M, Cummings C, Yu L, Wang ZM, Zink D, Ng Z, Loo SCJ,Ng KW. The multi-facets of sustainable nanotechnology-Lessons from a nanosafety symposium. Nanotoxicology 9, 404-406, (2015) [https://doi.org/10.3109/17435390.2015.1027315].
  12. Bhardwaj N, Ting Sow W, Devi D, Woei Ng K, Mandal BB,Cho NJ. Erratum: Silk fibroin-keratin based 3D scaffolds as a dermal substitute for skin tissue engineering (Integrative Biology (United Kingdom) (2015) DOI: 10.1039/c4ib00208c). Integrative Biology (United Kingdom) 7, 142, (2015) [https://doi.org/10.1039/c4ib90045f].
  13. Bhardwaj N, Sow WT, Devi D, Ng KW, Mandal BB,Cho NJ. Silk fibroin-keratin based 3D scaffolds as a dermal substitute for skin tissue engineering. Integrative Biology (United Kingdom) 7, 53-63, (2015) [https://doi.org/10.1039/c4ib00208c].
  14. Low YKA, Zou X, Fang YM, Wang JL, Lin WS, Boey FYC,Ng KW. β-Phase poly(vinylidene fluoride) films encouraged more homogeneous cell distribution and more significant deposition of fibronectin towards the cell-material interface compared to α-phase poly(vinylidene fluoride) films. Materials Science and Engineering C 34, 345-353, (2014) [https://doi.org/10.1016/j.msec.2013.09.029].
  15. Leong DT,Ng KW. Probing the relevance of 3D cancer models in nanomedicine research. Advanced Drug Delivery Reviews 79, 95-106, (2014) [https://doi.org/10.1016/j.addr.2014.06.007].
  16. Zhao Y, Ma X, Qu Q, Zhao Y, Luo Z, Zhao Y,Ng KW. Graphene oxide wrapped gold nanoparticles for intracellular Raman imaging and drug delivery. Journal of Materials Chemistry B 1, 6495-6500, (2013) [https://doi.org/10.1039/c3tb21385d].
  17. Zhao Y, Howe JLC, Yu Z, Leong DT, Chu JJH, Loo JSC,Ng KW. Exposure to titanium dioxide nanoparticles induces autophagy in primary human keratinocytes. Small 9, 387-392, (2013) [https://doi.org/10.1002/smll.201201363].
  18. Zhao X, Ong KJ, Ede JD, Stafford JL, Ng KW, Goss GG,Loo SCJ. Evaluating the toxicity of hydroxyapatite nanoparticles in catfish cells and zebrafish embryos. Small 9, 1734-1741, (2013) [https://doi.org/10.1002/smll.201200639].
  19. Zhao X, Ng S, Heng BC, Guo J, Ma L, Tan TTY, Ng KW,Loo SCJ. Cytotoxicity of hydroxyapatite nanoparticles is shape and cell dependent. Archives of Toxicology 87, 1037-1052, (2013) [https://doi.org/10.1007/s00204-012-0827-1].
  20. Yu H, Lui YS, Xiong S, Leong WS, Wen F, Nurkahfianto H, Rana S, Leong DT, Ng KW,Tan LP. Insights into the role of focal adhesion modulation in myogenic differentiation of human mesenchymal stem cells. Stem Cells and Development 22, 136-147, (2013) [https://doi.org/10.1089/scd.2012.0160].
  21. Xiong S, Tang Y, Ng HS, Zhao X, Jiang Z, Chen Z, Ng KW,Loo SCJ. Specific surface area of titanium dioxide (TiO2) particles influences cyto- and photo-toxicity. Toxicology 304, 132-140, (2013) [https://doi.org/10.1016/j.tox.2012.12.015].
  22. Xiong S, George S, Yu H, Damoiseaux R, France B, Ng KW,Loo JSC. Size influences the cytotoxicity of poly (lactic-co-glycolic acid) (PLGA) and titanium dioxide (TiO2) nanoparticles. Archives of Toxicology 87, 1075-1086, (2013) [https://doi.org/10.1007/s00204-012-0938-8].
  23. Xiong S, George S, Ji Z, Lin S, Yu H, Damoiseaux R, France B, Ng KW,Loo SCJ. Size of TiO2 nanoparticles influences their phototoxicity: An in vitro investigation. Archives of Toxicology 87, 99-109, (2013) [https://doi.org/10.1007/s00204-012-0912-5].
  24. Wu YL, Putcha N, Ng KW, Leong DT, Lim CT, Loo SCJ,Chen X. Biophysical responses upon the interaction of nanomaterials with cellular interfaces. Accounts of Chemical Research 46, 782-791, (2013) [https://doi.org/10.1021/ar300046u].
  25. Tay CY, Fang W, Setyawati MI, Sum CP, Xie J, Ng KW, Chen X, Hong CHL,Leong DT. Reciprocal response of human oral epithelial cells to internalized silica nanoparticles. Particle and Particle Systems Characterization 30, 784-793, (2013) [https://doi.org/10.1002/ppsc.201300111].
  26. Sow WT, Lui YS,Ng KW. Electrospun human keratin matrices as templates for tissue regeneration. Nanomedicine 8, 531-541, (2013) [https://doi.org/10.2217/nnm.13.38].
  27. Setyawati MI, Tay CY, Chia SL, Goh SL, Fang W, Neo MJ, Chong HC, Tan SM, Loo SCJ, Ng KW, Xie JP, Ong CN, Tan NS,Leong DT. Titanium dioxide nanomaterials cause endothelial cell leakiness by disrupting the homophilic interaction of VE-cadherin. Nature Communications 4, (2013) [https://doi.org/10.1038/ncomms2655].
  28. Setyawati MI, Khoo PKS, Eng BH, Xiong S, Zhao X, Das GK, Tan TTY, Loo JSC, Leong DT,Ng KW. Cytotoxic and genotoxic characterization of titanium dioxide, gadolinium oxide, and poly(lactic-co-glycolic acid) nanoparticles in human fibroblasts. Journal of Biomedical Materials Research – Part A 101 A, 633-640, (2013) [https://doi.org/10.1002/jbm.a.34363].
  29. Ma X, Zhao Y, Ng KW,Zhao Y. Integrated hollow mesoporous silica nanoparticles for target drug/siRNA co-delivery. Chemistry – A European Journal 19, 15593-15603, (2013) [https://doi.org/10.1002/chem.201302736].
  30. Low YKA, Tan LY, Tan LP, Boey FYC,Ng KW. Increasing solvent polarity and addition of salts promote β-phase poly(vinylidene fluoride) formation. Journal of Applied Polymer Science 128, 2902-2910, (2013) [https://doi.org/10.1002/app.38451].
  31. Li H, Wong YS, Wen F, Ng KW, Ng GKL, Venkatraman SS, Boey FYC,Tan LP. Human Mesenchymal Stem-Cell Behaviour On Direct Laser Micropatterned Electrospun Scaffolds with Hierarchical Structures. Macromolecular Bioscience 13, 299-310, (2013) [https://doi.org/10.1002/mabi.201200318].
  32. Kathawala MH, Xiong S, Richards M, Ng KW, George S,Loo SCJ. Emerging in vitro models for safety screening of high-volume production nanomaterials under environmentally relevant exposure conditions. Small 9, 1504-1520, (2013) [https://doi.org/10.1002/smll.201201452].
  33. Ho VHB, Guo WM, Huang CL, Ho SF, Chaw SY, Tan EY, Ng KW,Loo JSC. Manipulating magnetic 3D spheroids in hanging drops for applications in tissue engineering and drug screening. Advanced Healthcare Materials 2, 1430-1434, (2013) [https://doi.org/10.1002/adhm.201200408].
  34. Wang S, Taraballi F, Tan LP,Ng KW. Human keratin hydrogels support fibroblast attachment and proliferation in vitro. Cell and Tissue Research 347, 795-802, (2012) [https://doi.org/10.1007/s00441-011-1295-2].
  35. Taraballi F, Wang S, Li J, Lee FYY, Venkatraman SS, Birch WR, Teoh SH, Boey FYC,Ng KW. Understanding the nano-topography changes and cellular influences resulting from the surface adsorption of human hair keratins. Advanced Healthcare Materials 1, 513-519, (2012) [https://doi.org/10.1002/adhm.201200043].
  36. Li H, Wen F, Wong YS, Boey FYC, Subbu VS, Leong DT, Ng KW, Ng GKL,Tan LP. Direct laser machining-induced topographic pattern promotes up-regulation of myogenic markers in human mesenchymal stem cells. Acta Biomaterialia 8, 531-539, (2012) [https://doi.org/10.1016/j.actbio.2011.09.029].
  37. Zhao X, Heng BC, Xiong S, Guo J, Tan TTY, Boey FYC, Ng KW,Loo JSC. In vitro assessment of cellular responses to rod-shaped hydroxyapatite nanoparticles of varying lengths and surface areas. Nanotoxicology 5, 182-194, (2011) [https://doi.org/10.3109/17435390.2010.503943].
  38. Xiong S, Zhao X, Heng BC, Ng KW,Loo JSC. Cellular uptake of Poly-(D,L-lactide-co-glycolide) (PLGA) nanoparticles synthesized through solvent emulsion evaporation and nanoprecipitation method. Biotechnology Journal 6, 501-508, (2011) [https://doi.org/10.1002/biot.201000351].
  39. Tay CY, Pal M, Yu H, Leong WS, Tan NS, Ng KW, Venkatraman S, Boey F, Leong DT,Tan LP. Bio-inspired micropatterned platform to steer stem cell differentiation. Small 7, 1416-1421, (2011) [https://doi.org/10.1002/smll.201002298].
  40. Ng KW, Khoo SPK, Heng BC, Setyawati MI, Tan EC, Zhao X, Xiong S, Fang W, Leong DT,Loo JSC. The role of the tumor suppressor p53 pathway in the cellular DNA damage response to zinc oxide nanoparticles. Biomaterials 32, 8218-8225, (2011) [https://doi.org/10.1016/j.biomaterials.2011.07.036].
  41. Ng KW, Abraham MC, Leong DTW, Morris C,Schantz J. Primary Culture of Specific Cell Types and the Establishment of Cell Lines. Animal Cell Culture: Essential Methods https://doi.org/10.1002/9780470669815.ch7, 205-230, (2011) [https://doi.org/10.1002/9780470669815.ch7].
  42. Menéndez S, Goh AM, Camus S, Ng KW, Kua N, Badal V,Lane DP. MDM4 downregulates p53 transcriptional activity and response to stress during differentiation. Cell Cycle 10, 1100-1108, (2011) [https://doi.org/10.4161/cc.10.7.15090].
  43. Low YKA, Meenubharathi N, Niphadkar ND, Boey FYC,Ng KW. α- and β-poly (vinylidene fluoride) evoke different cellular behaviours. Journal of Biomaterials Science, Polymer Edition 22, 1651-1667, (2011) [https://doi.org/10.1163/092050610X519471].
  44. Heng BC, Zhao X, Xiong S, Ng KW, Boey FYC,Loo JSC. Cytotoxicity of zinc oxide (ZnO) nanoparticles is influenced by cell density and culture format. Archives of Toxicology 85, 695-704, (2011) [https://doi.org/10.1007/s00204-010-0608-7].
  45. Heng BC, Zhao X, Tan EC, Khamis N, Assodani A, Xiong S, Ruedl C, Ng KW,Loo JSC. Evaluation of the cytotoxic and inflammatory potential of differentially shaped zinc oxide nanoparticles. Archives of Toxicology 85, 1517-1528, (2011) [https://doi.org/10.1007/s00204-011-0722-1].