Publications

Selected publications 

Eleanor Martin, Rossana Girardello, Gunnar Dittmar, and Alexander Ludwig. Time-resolved proximity proteomics uncovers a membrane tension-sensitive caveolin-1 interactome at the rear of migrating cells. Elife. 2024 Sep 24;13:e85601. https://doi.org/10.7554/eLife.85601. 

Alexander Ludwig. Protein droplets spread to seal tight junctions. News and Views commentary. Nature. 2024 Aug;632(8025):506-507. DOI: 10.1038/d41586-024-02234-7.

Ann-Christin Groh, Annika Möller-Kerutt, Kevin Gilhaus, Verena Höffken, Pavel Nedvetsky, Simon Kleimann, Malina Behrens, Sujasha Ghosh, Uwe Hansen, Michael P. Krahn, Klaus Ebnet, Hermann Pavenstädt, Alexander Ludwig, and Thomas Weide. PALS1 is a key regulator for the lateral distribution of tight junction proteins in renal epithelial cells. J Cell Sci. 137, jcs261303. doi:10.1242/jcs.261303. https://doi.org/10.1242/jcs.261303.

Thuan Beng Saw, Xumei Gao, Jianan He, Anh Phuong Le, Supatra Marsh, Keng-hui Lin, Alexander Ludwig, Jacques Prost, Chwee Teck Lim. Transepithelial potential difference governs epithelial homeostasis by electromechanics. Nature Physics. Published: July 28 2022. https://www.nature.com/articles/s41567-022-01657-1

Stine K Morthorst, Camilla Nielsen, Pietro Farinelli, Zeinab Anvarian, Christina B. R. Rasmussen, Andrea Serra-Marques, Ilya Ilya Grigoriev, Maarten Altelaar, Nicoline Furstenberg, Alexander Ludwig, Anna Akhmanova, Soren T Christensen, and Lotte Bang Pedersen. Angiomotin isoform 2 promotes binding of PALS1 to KIF13B at the base of primary cilia and suppresses ciliary elongation. J Cell Sci. 2022 Jun 8; jcs.259471. DOI: 10.1242/jcs.259471.

Barbara Hübner, Eric von Otter, Bilal Ahsan, Mei Ling Wee, Sara Henriksson, Alexander Ludwig and Sara Sandin. Ultrastructure and nuclear architecture of telomeric chromatin revealed by correlative light and electron microscopy. Nucleic Acids Research. Published: April 30, 2022. https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkac309/6576360.

Ronni A. G. da Silva, Wei Hong Tay, Foo Kiong Ho, Frederick Reinhart Tanoto, Kelvin K. L. Chong, Pei Yi Choo, Alexander Ludwig, Kimberly A. Kline. Enterococcus faecalis alters endo-lysosomal trafficking to replicate and persist within mammalian cells. PLoS Pathogens. Published: April 7, 2022. https://doi.org/10.1371/journal.ppat.1010434.

Martin, E, Girardello, R, Dittmar, G, Ludwig, A. New insights into the organisation and regulation of the apical polarity network in mammalian epithelial cells. Review. FEBS Journal. January 14, 2021. https://doi.org/10.1111/febs.15710.

Tan, B, Yatim, SMJM, Peng, S, Gunaratne, J, Hunziker, W, and Ludwig, A. The mammalian Crumbs complex defines a distinct polarity domain apical of epithelial tight junctions. Current Biology. Published June 11 2020. https://doi.org/10.1016/j.cub.2020.05.032.
See also the corresponding BioRxiv preprint: Tan, B, Peng, S, Sandin, S, Gunaratne, J, Hunziker, W, and Ludwig, A. Quantitative proximity proteomics resolves the epithelial apical-lateral border and uncovers a vertebrate marginal zone defined by the polarity protein Pals1. DOI: https://doi.org/10.1101/710202.
Tan, B, Peng, S, Yatim, SMJM, Gunaratne, J, Hunziker, W, and Ludwig, A. An optimised protocol for proximity biotinylation in confluent epithelial cell cultures using the peroxidase APEX2. STAR Protocols (2020). https://doi.org/10.1016/j.xpro.2020.100074.
Ludwig, A. Selective Visualization of caveolae by TEM using APEX2. Caveolae – Methods and Protocols. Methods in Molecular Biology. 2020;2169:1-10. https://doi.org/10.1007/978-1-0716-0732-9.
Tie HC, Ludwig A, Sandin S, Lu L. The Spatial Separation of Processing and Transport Functions to the Interior and Periphery of the Golgi Stack. eLife. 2018 Nov 30;7. pii: e41301. https://doi.org/10.7554/eLife.41301.
Ludwig A, Nguyen TH, Leong D, Ravi LI, Huan TB, Sandin S, and Sugrue R. 2017. Caveolae provide a specialized membrane environment for respiratory syncytial virus assembly. J Cell Sci. 2017 Feb 2. https://doi.org/10.1242/jcs.198853.
Ludwig A, Nichols BJ, Sandin S. Architecture of the Caveolar Coat Complex, J Cell Sci, 2016 Jul. DOI: https://doi.org/10.1242/jcs.191262.
Shvetz E, Ludwig A, Nichols BJ. News from the caves: update on the structure and function of caveolae. Curr. Opin. Cell Biol. 2014 Jun 5; 29C:99-106. https://doi.org/10.1016/j.ceb.2014.04.011.
Ludwig A, Howard G, Mendoza-Topaz C, Deerinck T, Mackey M, Sandin S, Ellisman MH, and Nichols B. Molecular Composition and Ultrastructure of the Caveolar Coat Complex. PLoS Biology. 2013 Aug;11 (8), e1001640. https://doi.org/10.1371/journal.pbio.1001640.

Selected publications 

Ann-Christin Groh, Annika Möller-Kerutt, Kevin Gilhaus, Verena Höffken, Pavel Nedvetsky, Simon Kleimann, Malina Behrens, Sujasha Ghosh, Uwe Hansen, Michael P. Krahn, Klaus Ebnet, Hermann Pavenstädt, Alexander Ludwig, and Thomas Weide. PALS1 is a key regulator for the lateral distribution of tight junction proteins in renal epithelial cells. J Cell Sci. 137, jcs261303. doi:10.1242/jcs.261303. https://doi-org.remotexs.ntu.edu.sg/10.1242/jcs.261303.

Thuan Beng Saw, Xumei Gao, Jianan He, Anh Phuong Le, Supatra Marsh, Keng-hui Lin, Alexander Ludwig, Jacques Prost, Chwee Teck Lim. Transepithelial potential difference governs epithelial homeostasis by electromechanics. Nature Physics. Published: July 28 2022. https://www.nature.com/articles/s41567-022-01657-1

Stine K Morthorst, Camilla Nielsen, Pietro Farinelli, Zeinab Anvarian, Christina B. R. Rasmussen, Andrea Serra-Marques, Ilya Ilya Grigoriev, Maarten Altelaar, Nicoline Furstenberg, Alexander Ludwig, Anna Akhmanova, Soren T Christensen, and Lotte Bang Pedersen. Angiomotin isoform 2 promotes binding of PALS1 to KIF13B at the base of primary cilia and suppresses ciliary elongation. J Cell Sci. 2022 Jun 8; jcs.259471. doi: 10.1242/jcs.259471.

Barbara Hübner, Eric von Otter, Bilal Ahsan, Mei Ling Wee, Sara Henriksson, Alexander Ludwig and Sara Sandin. Ultrastructure and nuclear architecture of telomeric chromatin revealed by correlative light and electron microscopy. Nucleic Acids Research. Published: April 30, 2022. https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkac309/6576360.

Ronni A. G. da Silva, Wei Hong Tay, Foo Kiong Ho, Frederick Reinhart Tanoto, Kelvin K. L. Chong, Pei Yi Choo, Alexander Ludwig, Kimberly A. Kline. Enterococcus faecalis alters endo-lysosomal trafficking to replicate and persist within mammalian cells. PLoS Pathogens. Published: April 7, 2022. https://doi.org/10.1371/journal.ppat.1010434.

Martin, E, Girardello, R, Dittmar, G, Ludwig, A. New insights into the organisation and regulation of the apical polarity network in mammalian epithelial cells. Review. FEBS Journal. January 14, 2021.https://doi.org/10.1111/febs.15710.

Tan, B, Yatim, SMJM, Peng, S, Gunaratne, J, Hunziker, W, and Ludwig, A. The mammalian Crumbs complex defines a distinct polarity domain apical of epithelial tight junctions. Current Biology. Published June 11 2020. https://doi.org/10.1016/j.cub.2020.05.032.
See also the corresponding BioRxiv preprint: Tan, B, Peng, S, Sandin, S, Gunaratne, J, Hunziker, W, and Ludwig, A. Quantitative proximity proteomics resolves the epithelial apical-lateral border and uncovers a vertebrate marginal zone defined by the polarity protein Pals1. doi: https://doi.org/10.1101/710202.
Tan, B, Peng, S, Yatim, SMJM, Gunaratne, J, Hunziker, W, and Ludwig, A. An optimised protocol for proximity biotinylation in confluent epithelial cell cultures using the peroxidase APEX2. STAR Protocols (2020). https://doi.org/10.1016/j.xpro.2020.100074.
Ludwig, A. Selective Visualization of caveolae by TEM using APEX2. Caveolae – Methods and Protocols. Methods in Molecular Biology. 2020;2169:1-10. https://doi.org/10.1007/978-1-0716-0732-9.
Tie HC, Ludwig A, Sandin S, Lu L. The Spatial Separation of Processing and Transport Functions to the Interior and Periphery of the Golgi Stack. eLife. 2018 Nov 30;7. pii: e41301. https://doi.org/10.7554/eLife.41301.
Ludwig A, Nguyen TH, Leong D, Ravi LI, Huan TB, Sandin S, and Sugrue R. 2017. Caveolae provide a specialized membrane environment for respiratory syncytial virus assembly. J Cell Sci. 2017 Feb 2. https://doi.org/10.1242/jcs.198853.
Ludwig A, Nichols BJ, Sandin S. Architecture of the Caveolar Coat Complex, J Cell Sci, 2016 Jul. doi: https://doi.org/10.1242/jcs.191262.
Shvetz E, Ludwig A, Nichols BJ. News from the caves: update on the structure and function of caveolae. Curr. Opin. Cell Biol. 2014 Jun 5; 29C:99-106. https://doi.org/10.1016/j.ceb.2014.04.011.
Ludwig A, Howard G, Mendoza-Topaz C, Deerinck T, Mackey M, Sandin S, Ellisman MH, and Nichols B. Molecular Composition and Ultrastructure of the Caveolar Coat Complex. PLoS Biology. 2013 Aug;11 (8), e1001640. https://doi.org/10.1371/journal.pbio.1001640.
Ludwig A, Otto GP, Riento K, Hams E, Fallon PG, Nichols BJ. Flotillin microdomains interact with the cortical cytoskeleton to control uropod formation and neutrophil recruitment. J Cell Biol. 2010 Nov;15;191(4):771-81. https://doi.org/10.1083/jcb.201005140.

Selected publications 

Ann-Christin Groh, Annika Möller-Kerutt, Kevin Gilhaus, Verena Höffken, Pavel Nedvetsky, Simon Kleimann, Malina Behrens, Sujasha Ghosh, Uwe Hansen, Michael P. Krahn, Klaus Ebnet, Hermann Pavenstädt, Alexander Ludwig, and Thomas Weide. PALS1 is a key regulator for the lateral distribution of tight junction proteins in renal epithelial cells. J Cell Sci. 137, jcs261303. doi:10.1242/jcs.261303. https://doi-org.remotexs.ntu.edu.sg/10.1242/jcs.261303.

Thuan Beng Saw, Xumei Gao, Jianan He, Anh Phuong Le, Supatra Marsh, Keng-hui Lin, Alexander Ludwig, Jacques Prost, Chwee Teck Lim. Transepithelial potential difference governs epithelial homeostasis by electromechanics. Nature Physics. Published: July 28 2022. https://www.nature.com/articles/s41567-022-01657-1

Stine K Morthorst, Camilla Nielsen, Pietro Farinelli, Zeinab Anvarian, Christina B. R. Rasmussen, Andrea Serra-Marques, Ilya Ilya Grigoriev, Maarten Altelaar, Nicoline Furstenberg, Alexander Ludwig, Anna Akhmanova, Soren T Christensen, and Lotte Bang Pedersen. Angiomotin isoform 2 promotes binding of PALS1 to KIF13B at the base of primary cilia and suppresses ciliary elongation. J Cell Sci. 2022 Jun 8; jcs.259471. doi: 10.1242/jcs.259471.

Barbara Hübner, Eric von Otter, Bilal Ahsan, Mei Ling Wee, Sara Henriksson, Alexander Ludwig and Sara Sandin. Ultrastructure and nuclear architecture of telomeric chromatin revealed by correlative light and electron microscopy. Nucleic Acids Research. Published: April 30, 2022. https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkac309/6576360.

Ronni A. G. da Silva, Wei Hong Tay, Foo Kiong Ho, Frederick Reinhart Tanoto, Kelvin K. L. Chong, Pei Yi Choo, Alexander Ludwig, Kimberly A. Kline. Enterococcus faecalis alters endo-lysosomal trafficking to replicate and persist within mammalian cells. PLoS Pathogens. Published: April 7, 2022. https://doi.org/10.1371/journal.ppat.1010434.

Martin, E, Girardello, R, Dittmar, G, Ludwig, A. New insights into the organisation and regulation of the apical polarity network in mammalian epithelial cells. Review. FEBS Journal. January 14, 2021.https://doi.org/10.1111/febs.15710.

Tan, B, Yatim, SMJM, Peng, S, Gunaratne, J, Hunziker, W, and Ludwig, A. The mammalian Crumbs complex defines a distinct polarity domain apical of epithelial tight junctions. Current Biology. Published June 11 2020. https://doi.org/10.1016/j.cub.2020.05.032.
See also the corresponding BioRxiv preprint: Tan, B, Peng, S, Sandin, S, Gunaratne, J, Hunziker, W, and Ludwig, A. Quantitative proximity proteomics resolves the epithelial apical-lateral border and uncovers a vertebrate marginal zone defined by the polarity protein Pals1. doi: https://doi.org/10.1101/710202.
Tan, B, Peng, S, Yatim, SMJM, Gunaratne, J, Hunziker, W, and Ludwig, A. An optimised protocol for proximity biotinylation in confluent epithelial cell cultures using the peroxidase APEX2. STAR Protocols (2020). https://doi.org/10.1016/j.xpro.2020.100074.
Ludwig, A. Selective Visualization of caveolae by TEM using APEX2. Caveolae – Methods and Protocols. Methods in Molecular Biology. 2020;2169:1-10. https://doi.org/10.1007/978-1-0716-0732-9.
Tie HC, Ludwig A, Sandin S, Lu L. The Spatial Separation of Processing and Transport Functions to the Interior and Periphery of the Golgi Stack. eLife. 2018 Nov 30;7. pii: e41301. https://doi.org/10.7554/eLife.41301.
Ludwig A, Nguyen TH, Leong D, Ravi LI, Huan TB, Sandin S, and Sugrue R. 2017. Caveolae provide a specialized membrane environment for respiratory syncytial virus assembly. J Cell Sci. 2017 Feb 2. https://doi.org/10.1242/jcs.198853.
Ludwig A, Nichols BJ, Sandin S. Architecture of the Caveolar Coat Complex, J Cell Sci, 2016 Jul. doi: https://doi.org/10.1242/jcs.191262.
Shvetz E, Ludwig A, Nichols BJ. News from the caves: update on the structure and function of caveolae. Curr. Opin. Cell Biol. 2014 Jun 5; 29C:99-106. https://doi.org/10.1016/j.ceb.2014.04.011.
Ludwig A, Howard G, Mendoza-Topaz C, Deerinck T, Mackey M, Sandin S, Ellisman MH, and Nichols B. Molecular Composition and Ultrastructure of the Caveolar Coat Complex. PLoS Biology. 2013 Aug;11 (8), e1001640. https://doi.org/10.1371/journal.pbio.1001640.
Ludwig A, Otto GP, Riento K, Hams E, Fallon PG, Nichols BJ. Flotillin microdomains interact with the cortical cytoskeleton to control uropod formation and neutrophil recruitment. J Cell Biol. 2010 Nov;15;191(4):771-81. https://doi.org/10.1083/jcb.201005140.

Selected publications 

Ann-Christin Groh, Annika Möller-Kerutt, Kevin Gilhaus, Verena Höffken, Pavel Nedvetsky, Simon Kleimann, Malina Behrens, Sujasha Ghosh, Uwe Hansen, Michael P. Krahn, Klaus Ebnet, Hermann Pavenstädt, Alexander Ludwig, and Thomas Weide. PALS1 is a key regulator for the lateral distribution of tight junction proteins in renal epithelial cells. J Cell Sci. 137, jcs261303. doi:10.1242/jcs.261303. https://doi-org.remotexs.ntu.edu.sg/10.1242/jcs.261303.

Thuan Beng Saw, Xumei Gao, Jianan He, Anh Phuong Le, Supatra Marsh, Keng-hui Lin, Alexander Ludwig, Jacques Prost, Chwee Teck Lim. Transepithelial potential difference governs epithelial homeostasis by electromechanics. Nature Physics. Published: July 28 2022. https://www.nature.com/articles/s41567-022-01657-1

Stine K Morthorst, Camilla Nielsen, Pietro Farinelli, Zeinab Anvarian, Christina B. R. Rasmussen, Andrea Serra-Marques, Ilya Ilya Grigoriev, Maarten Altelaar, Nicoline Furstenberg, Alexander Ludwig, Anna Akhmanova, Soren T Christensen, and Lotte Bang Pedersen. Angiomotin isoform 2 promotes binding of PALS1 to KIF13B at the base of primary cilia and suppresses ciliary elongation. J Cell Sci. 2022 Jun 8; jcs.259471. doi: 10.1242/jcs.259471.

Barbara Hübner, Eric von Otter, Bilal Ahsan, Mei Ling Wee, Sara Henriksson, Alexander Ludwig and Sara Sandin. Ultrastructure and nuclear architecture of telomeric chromatin revealed by correlative light and electron microscopy. Nucleic Acids Research. Published: April 30, 2022. https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkac309/6576360.

Ronni A. G. da Silva, Wei Hong Tay, Foo Kiong Ho, Frederick Reinhart Tanoto, Kelvin K. L. Chong, Pei Yi Choo, Alexander Ludwig, Kimberly A. Kline. Enterococcus faecalis alters endo-lysosomal trafficking to replicate and persist within mammalian cells. PLoS Pathogens. Published: April 7, 2022. https://doi.org/10.1371/journal.ppat.1010434.

Martin, E, Girardello, R, Dittmar, G, Ludwig, A. New insights into the organisation and regulation of the apical polarity network in mammalian epithelial cells. Review. FEBS Journal. January 14, 2021.https://doi.org/10.1111/febs.15710.

Tan, B, Yatim, SMJM, Peng, S, Gunaratne, J, Hunziker, W, and Ludwig, A. The mammalian Crumbs complex defines a distinct polarity domain apical of epithelial tight junctions. Current Biology. Published June 11 2020. https://doi.org/10.1016/j.cub.2020.05.032.
See also the corresponding BioRxiv preprint: Tan, B, Peng, S, Sandin, S, Gunaratne, J, Hunziker, W, and Ludwig, A. Quantitative proximity proteomics resolves the epithelial apical-lateral border and uncovers a vertebrate marginal zone defined by the polarity protein Pals1. doi: https://doi.org/10.1101/710202.
Tan, B, Peng, S, Yatim, SMJM, Gunaratne, J, Hunziker, W, and Ludwig, A. An optimised protocol for proximity biotinylation in confluent epithelial cell cultures using the peroxidase APEX2. STAR Protocols (2020). https://doi.org/10.1016/j.xpro.2020.100074.
Ludwig, A. Selective Visualization of caveolae by TEM using APEX2. Caveolae – Methods and Protocols. Methods in Molecular Biology. 2020;2169:1-10. https://doi.org/10.1007/978-1-0716-0732-9.
Tie HC, Ludwig A, Sandin S, Lu L. The Spatial Separation of Processing and Transport Functions to the Interior and Periphery of the Golgi Stack. eLife. 2018 Nov 30;7. pii: e41301. https://doi.org/10.7554/eLife.41301.
Ludwig A, Nguyen TH, Leong D, Ravi LI, Huan TB, Sandin S, and Sugrue R. 2017. Caveolae provide a specialized membrane environment for respiratory syncytial virus assembly. J Cell Sci. 2017 Feb 2. https://doi.org/10.1242/jcs.198853.
Ludwig A, Nichols BJ, Sandin S. Architecture of the Caveolar Coat Complex, J Cell Sci, 2016 Jul. doi: https://doi.org/10.1242/jcs.191262.
Shvetz E, Ludwig A, Nichols BJ. News from the caves: update on the structure and function of caveolae. Curr. Opin. Cell Biol. 2014 Jun 5; 29C:99-106. https://doi.org/10.1016/j.ceb.2014.04.011.
Ludwig A, Howard G, Mendoza-Topaz C, Deerinck T, Mackey M, Sandin S, Ellisman MH, and Nichols B. Molecular Composition and Ultrastructure of the Caveolar Coat Complex. PLoS Biology. 2013 Aug;11 (8), e1001640. https://doi.org/10.1371/journal.pbio.1001640.
Ludwig A, Otto GP, Riento K, Hams E, Fallon PG, Nichols BJ. Flotillin microdomains interact with the cortical cytoskeleton to control uropod formation and neutrophil recruitment. J Cell Biol. 2010 Nov;15;191(4):771-81. https://doi.org/10.1083/jcb.201005140.

Selected publications 

Ann-Christin Groh, Annika Möller-Kerutt, Kevin Gilhaus, Verena Höffken, Pavel Nedvetsky, Simon Kleimann, Malina Behrens, Sujasha Ghosh, Uwe Hansen, Michael P. Krahn, Klaus Ebnet, Hermann Pavenstädt, Alexander Ludwig, and Thomas Weide. PALS1 is a key regulator for the lateral distribution of tight junction proteins in renal epithelial cells. J Cell Sci. 137, jcs261303. doi:10.1242/jcs.261303. https://doi-org.remotexs.ntu.edu.sg/10.1242/jcs.261303.

Thuan Beng Saw, Xumei Gao, Jianan He, Anh Phuong Le, Supatra Marsh, Keng-hui Lin, Alexander Ludwig, Jacques Prost, Chwee Teck Lim. Transepithelial potential difference governs epithelial homeostasis by electromechanics. Nature Physics. Published: July 28 2022. https://www.nature.com/articles/s41567-022-01657-1

Stine K Morthorst, Camilla Nielsen, Pietro Farinelli, Zeinab Anvarian, Christina B. R. Rasmussen, Andrea Serra-Marques, Ilya Ilya Grigoriev, Maarten Altelaar, Nicoline Furstenberg, Alexander Ludwig, Anna Akhmanova, Soren T Christensen, and Lotte Bang Pedersen. Angiomotin isoform 2 promotes binding of PALS1 to KIF13B at the base of primary cilia and suppresses ciliary elongation. J Cell Sci. 2022 Jun 8; jcs.259471. doi: 10.1242/jcs.259471.

Barbara Hübner, Eric von Otter, Bilal Ahsan, Mei Ling Wee, Sara Henriksson, Alexander Ludwig and Sara Sandin. Ultrastructure and nuclear architecture of telomeric chromatin revealed by correlative light and electron microscopy. Nucleic Acids Research. Published: April 30, 2022. https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkac309/6576360.

Ronni A. G. da Silva, Wei Hong Tay, Foo Kiong Ho, Frederick Reinhart Tanoto, Kelvin K. L. Chong, Pei Yi Choo, Alexander Ludwig, Kimberly A. Kline. Enterococcus faecalis alters endo-lysosomal trafficking to replicate and persist within mammalian cells. PLoS Pathogens. Published: April 7, 2022. https://doi.org/10.1371/journal.ppat.1010434.

Martin, E, Girardello, R, Dittmar, G, Ludwig, A. New insights into the organisation and regulation of the apical polarity network in mammalian epithelial cells. Review. FEBS Journal. January 14, 2021.https://doi.org/10.1111/febs.15710.

Tan, B, Yatim, SMJM, Peng, S, Gunaratne, J, Hunziker, W, and Ludwig, A. The mammalian Crumbs complex defines a distinct polarity domain apical of epithelial tight junctions. Current Biology. Published June 11 2020. https://doi.org/10.1016/j.cub.2020.05.032.
See also the corresponding BioRxiv preprint: Tan, B, Peng, S, Sandin, S, Gunaratne, J, Hunziker, W, and Ludwig, A. Quantitative proximity proteomics resolves the epithelial apical-lateral border and uncovers a vertebrate marginal zone defined by the polarity protein Pals1. doi: https://doi.org/10.1101/710202.
Tan, B, Peng, S, Yatim, SMJM, Gunaratne, J, Hunziker, W, and Ludwig, A. An optimised protocol for proximity biotinylation in confluent epithelial cell cultures using the peroxidase APEX2. STAR Protocols (2020). https://doi.org/10.1016/j.xpro.2020.100074.
Ludwig, A. Selective Visualization of caveolae by TEM using APEX2. Caveolae – Methods and Protocols. Methods in Molecular Biology. 2020;2169:1-10. https://doi.org/10.1007/978-1-0716-0732-9.
Tie HC, Ludwig A, Sandin S, Lu L. The Spatial Separation of Processing and Transport Functions to the Interior and Periphery of the Golgi Stack. eLife. 2018 Nov 30;7. pii: e41301. https://doi.org/10.7554/eLife.41301.
Ludwig A, Nguyen TH, Leong D, Ravi LI, Huan TB, Sandin S, and Sugrue R. 2017. Caveolae provide a specialized membrane environment for respiratory syncytial virus assembly. J Cell Sci. 2017 Feb 2. https://doi.org/10.1242/jcs.198853.
Ludwig A, Nichols BJ, Sandin S. Architecture of the Caveolar Coat Complex, J Cell Sci, 2016 Jul. doi: https://doi.org/10.1242/jcs.191262.
Shvetz E, Ludwig A, Nichols BJ. News from the caves: update on the structure and function of caveolae. Curr. Opin. Cell Biol. 2014 Jun 5; 29C:99-106. https://doi.org/10.1016/j.ceb.2014.04.011.
Ludwig A, Howard G, Mendoza-Topaz C, Deerinck T, Mackey M, Sandin S, Ellisman MH, and Nichols B. Molecular Composition and Ultrastructure of the Caveolar Coat Complex. PLoS Biology. 2013 Aug;11 (8), e1001640. https://doi.org/10.1371/journal.pbio.1001640.
Ludwig A, Otto GP, Riento K, Hams E, Fallon PG, Nichols BJ. Flotillin microdomains interact with the cortical cytoskeleton to control uropod formation and neutrophil recruitment. J Cell Biol. 2010 Nov;15;191(4):771-81. https://doi.org/10.1083/jcb.201005140.