Sierin Lim is an Associate Professor of Bioengineering at the School of Chemical and Biomedical Engineering and the Associate Dean (Global Partnerships) at the Graduate College. Her research group focuses on repurposing biological parts by utilizing protein engineering as a tool for applications in health and environment. She earned her B.S. in Chemical Engineering and Ph.D. in Biomedical Engineering from University of California Los Angeles (UCLA) and did a postdoc at University of California Irvine. She founded the Biomedical Engineering Society (Singapore) Student Chapter and Women@NTU Initiatives. She is the recipient of the L’Oréal-UNESCO Singapore for Women in Science National Fellowships (2013), Tan Chin Tuan Fellowship for Exchange in Engineering (2016), and Outstanding Woman in Biomedical Engineering Venus International Women Awards (2019).
Nature provides us with myriad biological building blocks that can be assembled and repurposed. Our group focuses on engineering these biological building blocks, particularly proteins and carbohydrates, and build systems for applications in health and environment. We derive design principles for building of the systems by combining the knowledge gained through in-depth bio and physicochemical studies with the exploration of real-life problems. We are also interested in multi-disciplinary approaches involving economics and art, as well as other aspects of humanities.
Engineering biology for health and environment
S Bhaskar, S Lim, “Engineering protein nanocages as carriers for biomedical applications”, NPG Asia Materials (2017) 9 (4), e371-e371; a comprehensive review of the work in the field.
M Sarker, H Lee, RA Gonçalves, YM Lam, H Su, S Lim, “Supramolecular Protein Assembly Retains Its Structural Integrity at Liquid–Liquid Interface”, Advanced Materials Interfaces (2020), 1901674; first report on in-depth study of the subject which was featured as inside back cover.
H Qiu, X Dong, B Sana, T Peng, D Paramelle, P Chen, S Lim. “Ferritin-Templated Synthesis and Self-Assembly of Pt Nanoparticles on a Monolithic Porous Graphene Network for Electrocatalysis in Fuel Cells”, ACS Applied Materials & Interfaces (2013) 5 (3), 782-787; interdisciplinary study involving biology and material science for application in energy.
Biological engineering towards carbon-neutral bio-upcycling; NTU, A*STAR, NUS
Bacterial cellulose for oral wound dressing; NTU and National Dental Center
Protein cages for imaging atherosclerotic plaques
POWERS: Promotion of Women in Engineering, Research, and Science; CoE, CoS, and psychology
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Associate Professor, School of Chemical and Biomedical Engineering, College of Engineering
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